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1. Schäfer M, Hengstler JG, Löffler S, Flesh P (1990) Isolation, identification and toxicological characterisation of TSS1, a new mycotoxin of the rosenane class. Mycotox Res 6: 21-30
2. Hengstler JG, Fuchs J, Oesch F (1992) DNA strand breaks and cross-links in peripheral mononuclear blood cells of human ovarian cancer patients during chemotherapy with cyclophosphamide/carboplatin. Cancer Res 52: 5622-5626
3. Hengstler JG, Löffler S, Schaefer M, Glatt HR, Fuchs J, Flesh P, Oesch F (1992) DNA strand break induction, mutagenicity, and cytotoxicity of the mycotoxins 11-ß-hydroxy-7-deoxy-rosenonolactone, rosenonolactone, and trichothecin, Mycotox Res 8: 77-83
4. Hengstler JG, Fuchs J, Gebhard S, Oesch F (1994) Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity. Mutation Res 304: 229-234
5. Fuchs J, Wullenweber U, Hengstler JG, Bienfait HG, Hiltl G, Oesch F (1994) Genotoxic risk for humans due to a working place exposure to ethylene oxide: remarkable individual differences in susceptibility. Arch Toxicol 68: 343-348
6. Oesch F, Hengstler JG, Fuchs J (1994) Cigarette smoking protects mononuclear blood cells of carcinogen exposed workers from additional work-exposure induced DNA single strand breaks. Mutat Res 321: 175-185
7. Dunkelberg H, Fuchs J, Hengstler JG, Klein E, Oesch F, Strüder K (1994) Genotoxic effects of the herbicides alachlor, atrazine, pendimethaline, and simazine in mammalian cells, Bull. Environ. Contam Toxicol 52: 498-504
8. Schuler M, Hengstler JG, Oesch F, Huber Ch (1994) Sekundäre Neoplasien des immunsupprimierten Patienten. Dtsch Med Wschr 119: 1747-1754
9. Hengstler JG, Fuchs J, Bolm-Audorff U, Meyer S, Oesch F (1995) DNA single strand breaks in fire fighters accidently exposed to o-nitroanisole and other chemicals. Scand J Work Environ. Health 21: 36-42
10. Fuchs J, Burg J, Hengstler JG, Bolm-Audorff U, Oesch F (1995) DNA damage in mononuclear blood cells of metal workers exposed to N-nitrosodiethanolamine in cutting fluids. Mutation Res 342: 95-102
11. Oesch F, Hengstler JG, Arand M, Fuchs J (1995) Detection of primary DNA damage: applicability to biomonitoring of genotoxic occupational exposure and in clinical therapy. Pharmacogenetics 5: 118-122
12. Fuchs J, Hengstler JG, Jung D, Hiltl G, Konietzko J, Oesch F (1995) DNA damage in nurses handling antineoplasitic agents. Mutation Res 342: 17-23
13. Oesch F, Fuchs J, Arand M, Vaupel J, Hengstler JG (1995) DNA single strand break analysis in mononuclear blood cells of gasoline station attendants. Int Arch Occup Environ. Health 67: 35-39
14. Fuchs J, Hengstler JG, Hummrich F, Oesch F (1996) Transient increase in DNA strand breaks in car refinishing spray painters. Scand J Work Environ. Health 22: 438-443
15. Arand M, Mühlbauer R, Hengstler JG, Jäger E, Fuchs J, Winkler L, Oesch F (1996) A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms. Anal Biochem 236: 184-186
16. Preuss I, Eberhagen I, Haas S, Eichhorn U, Kaufmann M, Beck T, Eibl RH, Dall P, Bauknecht T, Dippold W, Hengstler JG, Kaina B (1996) Activity of the DNA repair protein O6-methylguanine-DNA methyltransferase in human tumor and normal tissue. Cancer Det & Prev 20: 130-136
17. Fuchs J, Hengstler JG, Boettler G, Oesch F (1996) Primary DNA damage in peripheral mononuclear blood cells of workers exposed to bitumen-based products. Int Arch Occup Environ. Health 68: 141-146
18. Hengstler JG, Oesch F (1996) Control Mechanisms of Carcinogenesis in the publishing house of the editors. Mainz
19. Oesch F, Hengstler JG (1996) International symposium on control mechanisms of carcinogenesis: meeting report. J Cancer Res Clin Oncol 122: 374-378
20. Jung D, Clark G, Hengstler JG, Uhrig P, Edler L, Needham L, Lucier G, Patterson D, Oesch F, Konietzko J (1996) Ah-Rezeptor, Enzymaktivität und Dioxinspiegel. Forum DKG 11: 108-110
21. Hengstler JG, Hengst A, Fuchs J, Tanner B, Oesch F (1997) Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1. Mutation Res 372: 215-223
22. Hengstler JG, Bockisch A, Fuchs J, Grimm W, Zapf AO, Lade K, Tanner B, Oesch F (1997) Increase in DNA-single strand break rejoining by continuous exposure of human mononuclear blood cells to radioiodine (131I) in vitro. Int J Radiat Biol 72: 607-613
23. Hengstler JG, Fuchs J, Tanner B, Oesch-Bartlomowicz B, Hölz C, Oesch F (1997) Analysis of DNA single strand breaks in human venous blood: A technique which does not require isolation of white blood cells. Environmental and Molecular Mutagenesis 29: 58-62
24. Tanner B, Hengstler JG, Laubscher S, Meinert R, Oesch F, Knapstein PG, Becker R (1997) MDM2 mRNA expression is associated with survival in ovarian cancer. Int J Cancer 74: 1-5
25. Fritz G, Hengstler JG, Kaina B (1997) High-dose selection with mafosfamide results in sensitivity to DNA cross-linking agents: characterization of hypersensitive cell lines. Cancer Res 57: 454-460
26. Oesch-Bartlomowicz B, Arens HJ, Richter B, Hengstler JG, Oesch F (1997) Control of the mutagenicity of aromatic amines by protein kinases and phosphatases: I. The protein phosphatase inhibitors okadaic acid and ortho-vanadate drastically reduce the mutagenicity of aromatic amines. Arch Toxicol 71: 601-611
27. Tanner B, Hengstler JG, Dietrich B, Henrich M, Steinberg P, Weikel W, Meinert R, Kaina R, Oesch F, Knapstein PG (1997) Glutathione, Glutathione S-transferase a and p, and aldehyde dehydrogenase content in relationship to drug resistance in ovarian cancer. Gynecol Oncol 65: 54 - 62
28. Padma PR, Oesch-Bartlomowicz B, Hengstler JG, Oesch F (1997) Control of the mutagenicity of arylamines by protein kinases and phosphatases: II. Lack of response of rat liver N-acetyl transferases to phosphorylation modulators. Arch Toxicol 71: 655-659
29. Herrero ME, Arand M, Hengstler JG, Oesch F (1997) Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide-induced but not from ethylene oxide-induced DNA strand breaks. Environmental and Molecular Mutagenesis 30: 429-439
30. Oesch F, Fuchs J, Arand M, Gebhard S, Hallier A, Oesch-Bartlomowicz B, Jung D, Tanner B, Bolm-Audorff U, Hiltl G, Bienfait G, Konietzko J, Hengstler JG (1997) Möglichkeiten und Grenzen der alkalischen Filterelution zum Biomonitoring gentoxischer Belastungen. In: Molekulare Marker bei Beruflich Verursachten Tumoren, Hrsg.: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Berlin: 71-101
31. Hengstler JG, Oesch F (1997) Interspecies differences in xenobiotic metabolizing enzymes and their importance for interspecies extrapolation of toxicity. In: General and Applied Toxicology, eds.: Ballantyne B., Marrs T., and Syversen T., Volume 1: 271-290, Macmillan Reference LTD, London
32. Hengstler G, Kett A, Arand M, Oesch-Bartlomowicz B, Oesch F, Pilch H, Tanner B (1998) Glutathione S-transferase T1 and M1 gene defects in ovarian carcinoma. Cancer Letters 130: 43-48
33. Tanner B, Hengstler JG, Luch A, Meinert R, Kreutz E, Arand M, Wilkens C, Hofmann M, Oesch F Knapstein PG, Becker R (1998) C-myc mRNA expression in epithelial ovarian carcinomas in relation to estrogen receptor status, metastatic spread, survival time, FIGO stage, and histologic grade and type. Int J Gynecol Pathol 17: 66-74
34. Hengstler JG, Böttger T, Tanner B, Dietrich B, Henrich M, Knapstein PG, Junginger Th, Oesch F (1998) Resistance factors in colon cancer tissue and the adjacent normal colon tissue: Glutathione S-transferase a and p, glutathione, and aldehyde dehydrogenase. Cancer Letters 128: 105-112
35. Oesch-Bartlomowicz B, Padma PR, Becker R, Richter B, Hengstler JG, Freeman JE, Wolf R, Oesch F (1998) Differential modulation of CYP2E1 activity by cAMP-dependent protein kinase upon Ser129 replacement. Experimental Cell Research 242: 294-302
36. Kienast K, Drumm K, Hengstler JG, Smolarski R, Daum T, Grammann N, Carter J, Becker S, Devlin RB, Koren H (1998) Induction of superoxide dismutase (SOD) transcription and DNA strand lesions in alveolar macrophages after exposure to indoor relevant particles and fibers. In: ILSI Monographs: Relationships Between Respiratory Disease and Exposure to Air Pollution, ed.: U. Mohr: 361-365
37. Hengstler JG, Arand M, Herrero ME, Oesch F (1998) Polymorphisms of N-Acetyltransferases, Glutathione S-transferases, Microsomal Epoxide Hydrolase and Sulfotransferases: Influence on Cancer Susceptibility. In: Genes and Environment, ed.: Schwab M, Springer, New York. Recent Results Cancer Res 154: 47-85
38. Hengstler JG, Lange J, Kett A, Dornhöfer N, Meinert R, Arand M, Knapstein PG, Becker R, Oesch F and Tanner B (1999) Contribution of c-erbB-2 and topoisomerase IIa to chemoresistance in ovarian cancer. Cancer Res 59: 3206-3214
39. Hengstler JG, Bockisch A, Fuchs J, Grimm W, Görges R, Oesch-Bartlomowicz B, Zapf AO, Lade K, Tanner B, Teichmann E, Thelen M, Gebhard S, Oesch F (2000) Induction of DNA single strand breaks by 131I and 99Tcm in human mononuclear blood cells in vitro and extrapolation to the in vivo situation. Radiation Research 153: 512-520
40. Hengstler JG, Tanner B, Möller L, Vydra M, Oesch F, Meinert R, Kaina B (1999) Activity of O6-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer. Int J Cancer 84: 388-395
41. Kienast K, Kaes C, Drumm K, Buhl R, Oesch F, Hengstler JG (2000) Asbestos-exposed blood monocytes - deoxyribonucleic acid strand lesions in co-cultured bronchial epithelial cells. Scand J Work Environ. Health 26: 71-77
42. Schlink K, Janßen K, Nitzsche S, Gebhard S, Hengstler JG, Klein S, Oesch F (1999) Activity of O6-methylguanine DNA methyltransferase in mononuclear blood cells of formaldehyde-exposed medical students. Arch Toxicol 73: 15-21
43. Steinberg P, Fischer T, Kiulies S, Biefang K, Platt K-L, Oesch F, Böttger Th, Bulitta C, Kempf P, Hengstler JG (1999)Drug metabolizing capacity of cryopreserved human, rat and mouse liver parenchymal cells in suspension. Drug Metabolism and Disposition 27: 1415-1422
44. Strolin-Benedetti M, Brogin G, Bani M, Oesch F, Hengstler JG (1999) Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate. Xenobiotica 29: 1171-1180
45. Walgenbach S, Rosniatowski R, Bittinger F, Schicketanz KH, Hafner F, Hengstler J, Junginger T (1999) Modified cryopreservation and xenotransplantation of human parathyroid tissue. Langenbeck´s Arch Surg 384: 277-283
46. Schaeffer U, Strohschneider T, Pilch H, Hengstler JG, Tanner B, Stadtmüller A, Hannekum A (1999) Influence of several solutions used in bypass surgery on the permeability of the endothelium of carotid arteries in New Zealand rabbits. Thorac Cardiovasc Surg 47: 240-243
47. Hengstler JG, Walz J, Kübel R, Truong T, Fuchs J, Seidel A, Arand M, and Oesch F (1999) Enhancement of the mutagenicity of ethylene oxide and several directly acting mutagens by human erythrocytes and its reduction by xenobiotic interaction. In: Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, Kluwer Academic Plenum Publishers, edited by Arinc et al, New York: 221-246
48. Hengstler JG, Van der Burg B, Steinberg P, Oesch F (1999) Interspecies Differences in Cancer Susceptibility and Toxicity. Drug Metabolism Reviews 31: 917-970
49. Oesch F, Reifenrath M, Janßen K, Götte W, Jung D, Fuchs J, Gebhard S, Bienfait HG, Schlink K, Dietrich C, Faust D, Epe B, Bolm-Audorff U, Hengstler JG (1999) Berufliche Exposition gegenüber Kobalt und Cadmium: DNA-Schädigung und Hemmung der DNA-Reparatur. Symposium Medical 9: 30-31
50. Tanner B, Pilch H, Schmidt M, Steuer M, Schäffer U, Knapstein PG, Oesch F, Hengstler JG (1999) Correlation of c-erbB-2 and topoisomerase IIa mRNA expression in ovarian cancer. S. Pecorelli, G. Atlante, P. Benedetti, S. Mancuso, eds. International Gynecologic Cancer Society, Monduzzi Editore, Bologna: 303-310
51. Li AP, Gorycki PD, Hengstler JG, Kedderis GL, Koebe HG, Rahmani R, de Sousas G, Silva JM, Skett P (1999) Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel. Chem Biol Interact 121: 117-23
52. Hengstler JG, Ringel M, Biefang K, Hammel S, Milbert U, Gerl M, Klebach M, Diener B, Platt KL, Böttger T., Steinberg P, Oesch F (2000) Cultures with cryopreserved hepatocytes: applicability for studies of enzyme induction. Chemico Biological Interactions 125: 51-73
53. Hengstler JG, Bauer A, Wolf HK, Bulitta CJ, Tanner B, Oesch F, Boettger T (2000) Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer. Anticancer Research 20: 2967-2974
54. Oesch F, Herrero ME, Hengstler JG, Lohmann M, Arand M (2000) Metabolic detoxification: Implications for thresholds. Toxicologic Pathology 28: 382-387
55. Goodman JE, Lavigne JA, Hengstler JG, Tanner B, Helzlsouer KJ, Yager JD
(2000) Catechol-O-methyltransferase polymorphism is not associated with ovarian
cancer risk. Cancer Epidem Biomar 9: 1373-1376
56. Karim N, Allmeling C, Hengstler JG, Haverich A, Bader A (2000) Diazepam metabolism and albumin secretion of porcine hepatocytes in collagen-sandwich after cryopreservation. Biotechnology Letters 22: 1647-1652
57. Teichmann EM, Hengstler JG, Schreiber WG, Akbari W, Georgi H, Hehn M, Schiffer I, Oesch F, Spiess HW, Thelen M (2000) Mutagenic or co-mutagenic effect of magnetic fields in the Ames test. Rofo Fortschr Rontg 172: 934-939
58. Hengstler JG, Utesch D, Steinberg P, Ringel M, Swales N, Biefang K, Platt KL, Diener B, Böttger T, Fischer T, Oesch F (2000) Cryopreserved primary hepatocytes as an in vitro model for the evaluation of drug metabolism and enzyme induction. Drug Metabolism Reviews 32: 81-118
59. Oesch F, Arand M, Hengstler JG (2000) Enzympolymorphismen als Ursachen erhöhter Suszeptibilität in der chemischen Karzinogenese. In: Strahlenbiologie und Strahlenschutz, Individuelle Strahlenempfindlichkeit und Strahlenschutz. Publikationsreihe: Fortschritte im Strahlenschutz, eds.: W.U. Müller, G. Heinemann and F. Fehringer, Bad Kissingen, Band II: 374-393
60. Oesch-Bartlomowicz B, Richter B, Becker R, Vogel S, Padma PR, Hengstler JG, Oesch F (2001) cAMP-dependent phosphorylation of CYP2B1 as a functional switch for cyclophosphamide activation and its hormonal control in vitro and in vivo. Int J Cancer 94: 733-742
61. Bottger T, Kirsch D, Hengstler JG, Bauer A, Wolf HK, Junginger T (2001) Hereditary pancreatitis - A clinically relevant cause of pancreatic adenocarcinoma? Zbl Chir 126: 897-900
62. Romaneehsen B, Anders M, Rohrl B, Hengstler JG, Thelen M (2001) Cryotherapy of malignant tumors. MR imaging in comparison with pathological changes in mice. Rofo Fortschr Rontg 173: 632-638
63. Hengstler JG, Oesch F (2001) The Ames Test, Encyclopedia of Genetics, edited by Sydney Brenner and Jeffrey H. Miller. Academic Press, New York: 51-54
64. Oesch F, Herrero ME, Lohmann M, Hengstler JG, Arand M (2001) Sequestration of biologically reactive intermediates by trapping as covalent enzyme-intermediate complex. In: Biological Reactive Intermediates VI, ed.: R. Snyder, Kluwer Academic / Plenum Publishers, New York: 577-586
65. Hengstler JG, Pilch H, Schmidt M, Dahlenburg H, Sagemüller J, Schiffer I, Oesch F, Knapstein PG, Kaina B and B Tanner (2001) Metallothionein expression in ovarian cancer in relation to histopathologic parameters and molecular markers of prognosis. Int J Cancer 95: 121-127
66. Schreiber W, Teichmann E, Schiffer I, Hast J, Akbari W, Georgi H, Thelen M, Oesch F and Hengstler JG (2001) Lack of mutagenic and co-mutagenic effects of magnetic fields during magnetic resonance imaging, submitted.
67. Micke P, Hengstler JG, Ros R, Bittinger F, Metz T, Gebhard S, Beeh KM, Oesch F, Buhl R (2001) C-erbB-2 expression in small cell lung cancer is associated with poor prognosis. Int J Cancer 92: 474-479
68. Osterod M, Hollenbach S, Hengstler JG, Deborah EB, Lindahl T, Bernd E (2001) Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (ogg1) deficient mice. Carcinogenesis 22: 1459-1463
69. Ringel M, Oesch F, Bader A, Gerl M, Klebach M, Quint M, Tanner B, Dillenburg W, Böttger T, Hengstler JG (2002) Permissive and suppressive effects of dexamethasone on enzyme induction in hepatocyte cultures. Xenobiotica 32: 653-666
70. Hengstler JG, Janßen K, Jung D, Bienfait HG, Bolm-Audorff U, Fuchs J, Oesch F (2002) Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove cobalt as more dangerous then hitherto expected. Carcinogenesis
71. Lubec G, Gebhard S, Keßler H, Oesch F, Hengstler JG (2002) Increased DNA-protein crosslinking in brain of patients with Alzheimer disease. submitted.
72. Brenner W, Färber G, Herget T, Lehr H-A, Hengstler JG, Thüroff JW (2002) Loss of the tumor suppressor protein PTEN during renal carcinogenesis. Int J Cancer 99: 53-57
73. Beerheide W, von Mach MA, Ringel M, Fleckenstein C, Schumann S, Renzing N, Hildebrandt A, Brenner W, Jensen O, Gebhard S, Reifenberg K, Bender J, Oesch F, Hengstler JG (2002) Downregulation of beta2-microglobulin in human cord blood somatic stem cells after transplantation into livers of SCID-mice: an escape mechanism of stem cells? Biochemical Biophysical Research Communications 294: 1052-1063
74. Osterod M, Larsen E, Le Page F, Hengstler JG, Van Der Horst GT, Boiteux S, Klungland A, Epe B (2002) A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. Oncogene 28: 8232-8239
75. Micke P, Faldum A, Metz T, Beeh KM, Bittinger F, Hengstler JG, Buhl R (2002) Staging small cell lung cancer: Veterans Administration Lung Study Group versus International Association for the Study of Lung Cancer-what limits limited disease? Lung Cancer 37: 271-276
76. Vlachtsis K, Brieger J, Kim DW, Gieringer R, Hast J, Hengstler JG, Mann W (2002) Quantitative analysis of VEGF-isoforms in head and neck squamous cell carcinoma cell lines: relation to xenotransplantability and tumour progression in mice. Oncol Rep 9: 1133-1138
77. Tanner B, Pilch H, Schaffer U, Franzen A, Seufert R, Hengstler JG (2002) Expression of c-erbB-2 and topoisomerase II alpha in relation to chemoresistance in ovarian cancer. Zentralbl Gynakol 124: 176-83
78. Blaum K, Geppert C, Schreiber WG, Hengstler JG, Muller P, Nortershauser W, Wendt K, Bushaw BA (2002) Trace determination of gadolinium in biomedical samples by diode laser-based multi-step resonance ionization mass spectrometry. Anal Bioanal Chem 372: 759-65
79. Tanner B, Pilch H, Bahlmann F, Kaina B, Hengstler JG (2002) Activity of the DNA-repair enzyme O-6-methylguanine-DNA methytransferase in ovarian cancer. Geburtshilfe und Frauenheilkunde 62: 560-565
80. Brenner W, Färber G, Pahernik S, Lehr HA, Herget T, Hengstler JG, Thüroff JW (2002) Role of the tumorsuppressor PTEN in renal cell carcinomas. Act Urol
81. Tanner B, Pilch H, Schmidt M, Hengstler JG (2002) Expression of metallothionein and glutathione in ovarian carcinomas. German Journal of Obstetrics and Gynecology 62: 145-154
82. Hast J, Schiffer IB, Neugebauer B, Teichman E, Schreiber W, Brieger J, Kim DW, Gebhard S, Born CJ, Strugala M, Sagemuller J, Brenner W, Mann WJ, Oesch F, Thelen M, Hengstler JG (2002) Angiogenesis and fibroblast proliferation precede formation of recurrent tumors after radiation therapy in nude mice. Anticancer Res 22: 677-88
83. Hengstler JG, Ringel M, Böttger T., Oesch F (2003) Cryopreserved artificial liver organoides for studies of enzyme induction. submitted
84. Reder-Hilz B, Hengstler JG, Hewitt N, Utesch D, Ringel M, Oesch F, Ullrich M (2003) Metabolism of propafenone and verapamil by cryopreserved hepatocytes of human, rat, mouse, dog and monkey in relation to the in vivo situation. submitted
85. Micke P, Basrai M, Faldum A, Bittinger F, Ronnstrand L, Blaukat A, Beeh KM, Oesch F, Fischer B, Buhl R, Hengstler JG (2003) Characterization of c-kit Expression in Small Cell Lung Cancer: Prognostic and Therapeutic Implications. Clin Cancer Res 9: 188-94
86. Hengstler JG, Bolm-Audorff U, Faldum A, Janssen K, Reifenrath M, Gotte W, Jung D, Mayer-Popken O, Fuchs J, Gebhard S, Bienfait HG, Schlink K, Dietrich C, Faust D, Epe B, Oesch F (2003) Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. Carcinogenesis 24: 63-73
87. Schiffer IB, Gebhard S, Heimerdinger CK, Heling A, Hast J, Wollscheid U, Seliger B, Tanner B, Gilbert S, Beckers T, Baasner S, Brenner W, Sagemüller J, Spangenberg C, Prawitt D, Trost T, Schreiber WG, Zabel B, Thelen M, Oesch F and Hengstler JG (2003) Switching off HER-2/neu in a tetracycline controlled mouse tumor model leads to apoptosis and tumor-size dependent remission. Cancer Res
88. Hengstler JG, Bogdanffy MS, Bolt HM, Oesch F (2003) Challenging Dogma: Thresholds for Genotoxic Carcinogens? The case of Vinyl Acetate. Annu Rev Pharmacol Toxicol 43: 485-520
89. Von Mach MA, Lauterbach M, Kaes J, Hengstler JG, Weilemann LS (2003) Deliberate self-poisoning with paracetamol (acetaminophen). Dtsch Med Wochenschr 128: 15-9
90. Hengstler JG, Heimerdinger CK, Schiffer IB, Gebhard S, Sagemüller J, Tanner B, Bolt HM, Oesch F (2003) Dietary topoisomerase-II-poisons: Contribution of soy products to infant leucemia? Excli J 1: 8-14
91. Gebhardt R, Hengstler JG, Müller D, Glöckner R, Buenning P, Laube B, Schmelzer E, Ullrich M, Ringel M, Reder-Hilz B, Bader A, Koose T, Burger HJ, Maas J, Oesch F (2003, in press) New hepatocyte in vitro systems for drug metabolism: Metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metabolism Reviews
92. Arand M, Herrero Plana ME, Hengstler JG, Lohmann M, Cronin A, Oesch F (2003) Detoxification strategy of epoxide hydrolase the basis for a treshold in chemical carcinogenesis. Excli J 22: 22-30
93. Jung D, Bolm-Audorff U, Faldum A, Hengstler JG, Attia DI, Janssen K, Reifenrath M, Bienfait HG, Mayer-Popken O, Konietzko J (2003) Immunotoxicity of co-exposures to heavy metals: In vitro studies and results from occupational exposure to cadmium, cobalt and lead. Excli J 2: 31-44
94. Steiner E, Eicher O, Sagemuller J, Schmidt M, Pilch H, Tanner B, Hengstler JG, Hofmann M, Knapstein PG (2003) Multivariate independent factors in endometrial carcinoma: A clinicopathologic study in 181 patients: 10 years experience at the Department of Obstetrics and Gynecology of the Mainz University. Int J Gynecol Cancer 13: 197-203
95. von Mach MA, Schlosser J, Weiland M, Feilen PJ, Ringel M, Hengstler JG, Weilemann LS, Beyer J, Kann P, Schneider S (2003) Cryopreservation of islets of Langerhans: Optimization of protocols. Excli J 2: 6-21
96. Micke P, Basrai M, Faldum A, Bittinger F, Ronnstrand L, Blaukat A, Beeh KM, Oesch F, Fischer B, Buhl R, Hengstler JG (2003) Characterization of c-kit Expression in Small Cell Lung Cancer: Prognostic and Therapeutic Implications. Clin Cancer Res 9: 188-194
97. Hengstler JG, Bolm-Audorff U, Faldum A, Janssen K, Reifenrath M, Gotte W, Jung D, Mayer-Popken O, Fuchs J, Gebhard S, Bienfait HG, Schlink K, Dietrich C, Faust D, Epe B, Oesch F (2003) Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. Carcinogenesis 24: 63-73
98. Schiffer IB, Gebhard S, Heimerdinger CK, Heling A, Hast J, Wollscheid U, Seliger B, Tanner B, Gilbert S, Beckers T, Baasner S, Brenner W, Spangenberg C, Prawitt D, Trost T, Schreiber WG, Zabel B, Thelen M, Lehr HA, Oesch F, Hengstler JG (2003) Switching off her-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission (2003) Cancer Res 63: 7221-7231
99. Hengstler JG (2003) DNA damage induction and repair inhibition. Carcinogenesis 24: 1855-1857
100. Schiffer IB, Schreiber WG, Graf R, Schreiber EM, Jung D, Rose DM, Hehn M, Gebhard S, Sagemuller J, Spiess HW, Oesch F, Thelen M, Hengstler JG (2003) No influence of magnetic fields on cell cycle progression using conditions relevant for patients during MRI. Bioelectromagnetics 24: 241-250
101. Tanner B, Beerheide W, Jensen O, von Mach MA, Ringel M, Fleckenstein C, Schumann S, Renzing N, Hildebrand A, Neubert S, Glawatz C, Hengstler JG (2003) Isolation and transplantation of human mesenchymal stem cells from cord blood. Geburtsh.Frauenheilk. 63: 1040-1046
102. Hengstler JG, Heimerdinger C, Schiffer IB, Brulport M (2003) Toxikologie und Kanzerogenität: Gibt es einen Schwellenmechanismus? Forum DKG 6: 26-30
103. Steiner E, Eicher O, Sagemuller J, Schmidt M, Pilch H, Tanner B, Hengstler JG, Hofmann M, Knapstein PG (2003) Multivariate independent prognostic factors in endometrial carcinoma: A clinicopathologic study in 181 patients: 10 years experience at the Department of Obstetrics and Gynecology of the Mainz University. Int J Gynecol Cancer 13: 197-203
104. Efferth T, Sauerbrey A, Olbrich A, Gebhart E, Rauch P, Weber HO, Hengstler JG, Halatsch ME, Volm M, Tew KD, Ross DD, Funk JO (2003) Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol 64: 382-394
105. von Mach MA, Lauterbach M, Kaes J, Hengstler JG, Weilemann LS (2003) Deliberate self-poisoning with paracetamol (acetaminophen). Dtsch Med Wochenschr 128: 15-19
106. Gebhardt R, Hengstler JG, Müller D, Glöckner R, Buenning P, Laube B, Schmelzer E, Ullrich M, Utesch D, Hewitt N, Ringel M, Reder Hilz B, Bader A, Langsch A, Koose T, Burger HJ, Maas J, Oesch F (2003) New hepatocyte in vitro systems for drug metabolism: Metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metabolism Reviews 35: 145-213
107. Brenner W, Wiesner C, Färber G, Herget T, Hengstler JG, Thuroff JW (2003) Gender specific expression of tumor suppressor PKC"delta" versus oncogenic PKC"eta" in renal cell carcinoma. Excli J 2: 45-51
108. von Mach MA, Schlosser J, Weiland M, Feilen PJ, Ringel M, Hengstler JG, Weilemann LS, Beyer J, Kann P, Schneider S (2003) Size of pancreatic islets of Langerhans: a key parameter for viability after cryopreservation. Acta Diabetol. 40: 123-129
109. Arand M, Herrero Plana ME; Hengstler JG, Lohmann M, Cronin A, Oesch F (2003) Detoxification strategy of epoxide hydrolase the basis for a treshold in chemical carcinogenesis. Excli J 22: 22-30
110. Spangenberg C, Trost T, Lausch E, Fees S, Prawitt D, Hengstler JG, Sahin U, Tureci O, Zabel B (2003) Molecular analyses examining the consequences of reversible ERB82-expression in breast carcinoma cells. American Journal of Human Genetics 73: 500
111. Brenner W, Färber G, Herget T, Wiesner C, Hengstler JG, Thuroff JW (2003) Protein kinase C eta is associated with progression of renal cell carcinoma (RCC). Anticancer Res. 23: 4001-4006
112. Carmo H, Hengstler JG, De Boer D, Ringel M, Carvalho F, Fernandez E, Remiao F, Dos Reyes LA, Oesch F, De Lourdes Bastos M (2003) Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse. Naunyn Schmiedebergs Arch Pharmacol. Dec 16
113. Jung D, Bolm-Audorff U, Faldum A, Hengstler JG, Attia DI, Janssen K, Reifenrath M, Bienfait HG, Mayer-Popken O, Konietzko J (2003) Immunotoxictiy of co-exposures to heavy metals: In vitro studies and results from occupational exposure to cadmium, cobalt and lead. EXCLI J 2: 31-44
114. Graefe A, Müller RK, Hengstler JG (2003) 15 Jahre Postgradualstudium Toxikologie und Umweltschutz der Universität Leipzig von 1988 bis 2003. Privatdruck, Leipzig, S. 1-497.
115. Hengstler JG, Ringel M, Böttger T., Oesch F (2003) Cryopreserved artificial liver organoides for studies of enzyme induction.
116. Hengstler JG (2003) Letter to the editor. Carcinogenesis Sep
117. Oesch F und Hengstler JG (2004) Bedeutung des Metabolismus für die Risikoabschätzung. In: Reickel, Schwenk (Hrsg.) Regulatorische Toxikologie. Springer Heidelberg, 359-372
118. Mohrmann G, Hengstler JG, Hofmann TG, Endele SU, Lee B, Stelzer C, Zabel B, Brieger J, Schiffer I, Tanner B, Sagemueller J, Will H and Winterpacht A (in press) SPOC1, a novel nuclear PHD-finger protein, is a prognostic marker for ovarian carcinoma patient survival.
119. Reder-Hilz B, Ullrich M, Ringel M, Hewitt N, Utesch D, Oesch F, Hengstler JG (2004) Metabolism of propafenone and verapamil by cryopreserved human, rat mouse and dog hepatocytes: comparison with metabolism in vivo. Naunyn Schmiedebergs Arch Pharmacol 369: 408-417
120. Herrmann F, Lehr HA, Drexler I, Sutter G, Hengstler J, Wollscheid U, Seliger B (2004) HER-2/neu-Mediated Regulation of Components of the MHC Class I Antigen- Processing Pathway. Cancer Res. 64: 215-220
121. Tanner B, Grimme S, Schiffer I, Heimerdinger C, Schmidt M, Dutkowski P, Neubert S, Oesch F, Franzen A, Kolbl H, Fritz G, Kaina B, Hengstler JG (2004) Nuclear expression of apurinic/apyrimidinic endonuklease increases with progression of ovarian carcinomas. Gynecol Oncol 92: 568-577.
122. Carmo H, Hengstler JG, de Boer D, Ringel M, Carvalho F, Fernandes E, Remiao F, dos Reys LA, Oesch F, de Lourdes Bastos M (2004) Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse. Naunyn Schmiedebergs Arch Pharmacol 369: 198-205
123. Streffer C (Hrsg.), Bolt H, Follesdahl D, Hall P, Hengstler JG, Jakob P, Oughton D, Prieß K, Rehbinder E, Swaton E (2004) Low dose exposures in the environment. Springer, Heidelberg, S. 1-470 (ISBN: 3-540-21083-0)
124. Bolt HM, Foth H, Hengstler JG, Degen G (2004) Carcinogenicity categorization of chemicals – new aspects to be considered in a European perspective. Toxicology Letters 151: 29-41
125. Brenner W, Benzing F, Gudejko-Thiel J, Fischer R, Färber G, Hengstler JG, Seliger B, Thuroff JW (2004) Regulation of beta1-integrin expression by PKCepsilon in renal cancer cells. Int J Oncol 25: 1157-1163
126. Eger K, Hermes M, Uhlemann K, Rodewald S, Ortwein J, Brulport M, Bauer AW, Schormann W, Lupatsch F, Schiffer IB, Heimerdinger CK, Gebhard S, Spangenberg C, Prawitt D, Trost T, Zabel B, Sauer C, Tanner B, Kolbl H, Krugel U, Franke H, Illes P, Madaj-Sterba P, Bockamp EO, Beckers T, Hengstler JG (2004) 4-Epidoycycline: an alternative to doxycycline to control gene expression in conditional mouse models. Biochem Biophys Res Commun 323: 979-986
127. Kaina B, Hengstler JG (2004) Haben Karzinogene eine Schwellendosis? Pro und Contra. In: Reichel, Schwenk (Hrsg.) Regulatorische Toxikologie, Springer Heidelberg, S. 254-261
128. Micke P, Hengstler JG, Albrecht H, Faldum
A, Bittinger F, Becker K, Wiewrodt R,
Fischer B, Buhl R (2004) c-kit expression in adenocarcinomas of the lung. Tumour
Biol. 25: 235-242
129. Oesch F, Hengstler JG, Arand M (2004) Detoxification strategy of epoxide hydrolase – the basis for a novel threshold for definable genotoxic carcinogens. Nonlinearity in Biology, Toxicology and Medicine, 2: 21-26
130. von Mach MA, Hengstler JG, Brulport M, Eberhardt M, Schormann W, Hermes M, Prawitt D, Zabel B, Grosche J, Reichenbach A, Muller B, Weilemann LS, Zulewski H (2004) In vitro cultured islet-derived progenitor cells of human origin express human albumin in severe combined immunodeficiency mouse liver in vivo. Stem Cells 22, 1134-41
131. Carmo H, Hengstler JG, Boer D, Ringel M, Remiao F, Carvalho F, Fernandes E, Reys LA, Oesch F, Bastos M de L (2005) Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human. Toxicology, 206: 75-89
132. Mohrmann G, Hengstler JG, Hofmann TG, Endele SU, Lee B, Stelzer C, Zabel B, Brieger J, Schiffer I, Tanner B, Sagemueller J, Will H and Winterpacht A (in press) SPOC1, a novel nuclear PHD-finger protein, is a prognostic marker for ovarian carcinoma patient survival. Int J Cancer
133. Ringel M, von Mach MA, Santos R, Feilen PJ, Brulport M, Hermes M, Bauer AW, Schormann W, Tanner B, Schon MR, Oesch F, Hengstler JG (2005) Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction. Toxicology, 206: 153-67
134. Schupp T, Bolt HM, Hengstler JG (2005) Maximum exposure levels for xylene, formaldehyde and acetaldehyde in cars. Toxicology, 206: 461-70
135. Trost TM, Lausch EU, Fees SA, Schmitt S, Enklaar T, Reutzel D, Brixel LR, Schmidtke P, Maringer M, Schiffer IB, Heimerdinger CK, Hengstler JG, Fritz G, Bockamp EO, Prawitt D, Zabel BU, Spangenberg C (in press) Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells. Cancer Res
136. Hengstler JG (2004) Ausblick. In: Graefe
A, Müller RK, Kleemann WJ (Hrsg.) 100 Jahre Forensische Toxikologie im
Institut für Rechtsmedizin in Leipzig. MOLINA-press, Leipzig, S. 58-60
(ISBN 3-930865-05-X)